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Media contacts: For an embargoed PDF, please contact Cara Graeff. To reach the lead author David Studdert, LLB, ScD, please contact Beth Duff-Brown at email@example.com or 650-736-6064. 2. A routine invasive strategy may significantly reduce death risk in unstable angina M17-0947 URL goes live when the embargo lifts The absolute cumulative probability of death at 12 months was 5 percent lower for patients who received routine invasive coronary angiography and revascularization as indicated during an unstable angina admission compared to those who did not. The survival benefit persisted when angiography was delayed up to 2 months after the first unstable angina episode. Results of a comparative effectiveness analysis are published in Annals of Internal Medicine. Non-ST-segment elevation acute coronary syndromes consist of non-ST-segment elevation myocardial infarction (MI) and unstable angina. Reported rates of unstable angina have declined with the introduction of high-sensitivity troponin testing, which identifies patients with non-ST-segment elevation MI, yet patients with unstable angina still account for one-quarter to one-half of all those with acute coronary syndromes who present to the hospital. In general, current guidelines recommend routine invasive coronary angiography for patients with non-ST-segment elevation MI, but not for those with unstable angina. Meta-analyses of previous directory Oral Surgeon mortgage trials have shown conflicting results with regard to routine invasive management of unstable angina, potentially due to the high crossover from control to intervention groups in the randomized controlled trials. Researchers at St.